Cheapest GLP-1 Online: What Each Program Really Costs
Most pages that rank for this search repeat one list of prices from one source. We opened the programs' own sites and wrote down only what they publish, then marked what they leave out.
The short answer
On published numbers, ShedRx has the lowest ongoing starting price (GLP-1 from $159 a month, compounded tirzepatide from $239) and SkinnyRx advertises $99 for the first month. Those are entry prices for a dose you may not be prescribed. The price that counts is the one set after a clinician assesses what you need, which is why HumeCare+ shows it only after a free eligibility check.
Cheapest GLP-1 programs online: the prices they publish
Self-pay prices for compounded GLP-1 programs, read directly from each program's website on October 20, 2026. Where a program does not publish a number, the table says so instead of guessing.
| Program | What the site advertises | What to check |
|---|---|---|
| ShedRx | GLP-1 from $159 a month. Compounded tirzepatide from $239 a month. 120-day weight-loss guarantee (conditions apply). | "From" is the lowest-dose price. Higher doses are not shown on the pages we could read. |
| SkinnyRx | $99 for the first month of injectable semaglutide or tirzepatide, marked "while supplies last". Tirzepatide tablets $199 for the first month. | The price after month one is not published. It appears only after the medical questionnaire. |
| HumeCare+ | Shown after a free eligibility check, because the price follows the medication a clinician prescribes for you. Two independent price trackers list $199 a month (compounded semaglutide) and $299 a month (compounded tirzepatide with B12 and glycine), flat at every dose. | Your exact figure, in the free eligibility check, before you pay anything. |
Prices and promotions change often. This is a snapshot from October 20, 2026.
Why a price before the assessment is not a price you can compare
A GLP-1 is not a shelf product with one price. Which medication you are prescribed (semaglutide or tirzepatide), at what dose, and how fast it is raised depends on your health history, your goals and how you respond. A clinician decides that after reviewing your assessment.
That is why a "from $159" or "$99 first month" banner cannot be compared with a plan priced after the assessment. The banner describes the lowest dose of one medication, for a person nobody has assessed yet. A plan built around your assessment describes your treatment.
Seen this way, a program that asks what you need first and then gives you a price is doing what a prescription service should do. It is the same order of events as a doctor's visit: assessment, then plan, then cost.
Why the cheapest sticker is not always the cheapest total
A GLP-1 dose is raised over roughly the first three months. A price quoted at the lowest dose is a true number for month one and an incomplete number for month four. That is why two programs that look $40 apart on a landing page can finish a different way after six months.
Here is the comparison that works, and it takes five minutes:
- Ask for the price at the dose you will likely reach, not the starting dose.
- Add every fixed charge: consultation, shipping, membership, refill fees.
- Multiply by six months, then subtract only discounts you can actually keep after the intro period ends.
By that test, a flat price at every dose is worth more than a lower first-month price that climbs. It is also the reason the same headline number can mean different things at different programs. Our 9-point checklist for choosing a GLP-1 provider turns this into questions you can ask before you pay.
Cheapest GLP-1 without insurance
The programs above are self-pay and are not billed to insurance, Medicare or Medicaid. That is how most compounded GLP-1 programs work, and it is why they cost far less than brand-name medication paid out of pocket.
Compounded medications are prepared by a licensed pharmacy and are not FDA-approved for weight loss. Our guide is compounded tirzepatide legal and safe explains what that means, and how to verify a pharmacy's license with the state board.
Why HumeCare+ is the pick for a predictable price
The lowest starting figures above are priced at the lowest dose. HumeCare+ is the program built around a price that price trackers report as flat at every dose, so month four costs what month one did, and it includes what the cheaper listings do not mention:
- Body composition tracking with the Hume Pod, so you can see whether the weight you lose is fat or muscle, not only scale weight.
- A free eligibility check before you pay, with the membership fee refunded automatically if a clinician finds you are not eligible.
- Clinician support after enrollment for side effects and dose questions.
Our full HumeCare+ review covers the plan, the guarantee and the app in detail.
Free eligibility check on the official HumeCare+ site. If a clinician finds you are not eligible, the membership fee is refunded automatically.
Frequently asked questions
What is the cheapest GLP-1 online?
Among the programs we checked on their own sites on October 20, 2026, ShedRx shows the lowest ongoing starting price, from $159 a month for GLP-1 treatment and from $239 a month for compounded tirzepatide. SkinnyRx advertises $99 for the first month. Both are starting figures, and neither publishes what you pay at higher doses, so the cheapest sticker is not necessarily the cheapest total.
Who offers the cheapest GLP-1?
On published numbers, ShedRx (from $159 a month) and SkinnyRx ($99 first month) have the lowest entry prices. Two independent price trackers list HumeCare+ at $199 a month for compounded semaglutide and $299 for compounded tirzepatide, flat at every dose. The right answer depends on the dose you will reach, not the first month.
What is the cheapest GLP-1 without insurance?
Compounded GLP-1 programs are self-pay and are not billed to insurance, so they are the usual low-cost route without coverage. Prices in this guide are self-pay figures. Brand-name GLP-1 medications are priced much higher without insurance, and compounded versions are not FDA-approved for weight loss.
What is the cheapest compounded tirzepatide online?
ShedRx advertises compounded tirzepatide from $239 a month, and SkinnyRx advertises $99 for the first month of injectable tirzepatide. HumeCare+ is reported by price trackers at $299 a month for compounded tirzepatide with B12 and glycine. Compare the price at the dose you will reach, not the first month.
Is an affordable GLP-1 program safe?
Look for four things: a licensed clinician reviewing your assessment, licensed U.S. pharmacies preparing the medication, a clear statement that it is compounded, and a way to reach a clinician about side effects. HumeCare+ is built around all four, with a free eligibility check before you pay.
Why does HumeCare+ show the price only after the assessment?
Because the price follows the medication and plan a clinician prescribes for you, and that cannot be known before they review your assessment. It is the same order as a doctor visit: assessment first, then the plan, then the cost. The eligibility check is free, and the membership fee is refunded automatically if a clinician finds you are not eligible.
Why does the price change after the first month?
Many programs quote an introductory or lowest-dose price. GLP-1 doses are raised over the first few months, and at some providers the price rises with the dose. Ask for the total over six months at the dose you are likely to reach.
How much does a GLP-1 cost per month online?
From the programs we checked: from $159 a month at ShedRx, $99 for the first month at SkinnyRx, and $199 (semaglutide) or $299 (tirzepatide) a month for HumeCare+ according to price trackers. Prices and promotions change, so confirm the figure during the assessment before you pay.
Is HumeCare+ a cheap GLP-1 program?
HumeCare+ is built around a flat monthly price that price trackers report at every dose ($199 for compounded semaglutide, $299 for compounded tirzepatide), so month four costs what month one did. It also includes body composition tracking and a free eligibility check, with the membership fee refunded automatically if a clinician finds you ineligible.
Related reading
Before you enroll: HumeCare+ gives your exact price after the eligibility check, and its Terms list a consultation fee at enrollment and at each refill. Its money-back guarantee follows the 90-day conditions in the Terms (Section 8A), which are narrower than the homepage headline. The review linked above explains both.
This article is general information, not medical advice. Whether a GLP-1 is appropriate is a clinical decision that depends on your medical history.
Disclosure: this page contains an affiliate link to HumeCare+. If you sign up through it we may earn a commission at no extra cost to you. We earn nothing from the other programs listed, and their prices are shown exactly as they publish them. See our Editorial Policy.